NEW LINE of Unique products

[INSENSE3]

Thank y’all for 1) allowing this opportunity on this website. 2) Thank EVERYONE who works so hard to keep the site informative, safe and welcoming.
Definitely shout out to those serving people suffering with the virus!

Now fora flyer that may interest some folks (or not). I actually found the alternative botanicals in extract formula. I only got my order today. My order was placed on Wed and I have the package for personal “crash test dummy“ experiments and look forward to some botanicals I haven’t tried yet. Now in EXTRACT.

PLEASE take a moment to read about this unique (but becoming popular) product line for helping us all keep tolerance low:




Full Spectrum Alkaloids
This one is Potent...start with less

This Enhanced Blend is Real Kratom + Kratom "Extract" (which contains 10mg 45% Mitragynine Extract per 1g of powder).

Hi Everyone....

We carry some of the best Kratom around yet we find some people that just want/need stronger....
we have been headed this direction for a while but couldn't find a good enough supplier....Till Now.....

We just want everyone to know that we just added 4 strains or blends that are "Enhanced"....and Potent.

The nice thing is that ours are enhanced with Full Spectrum Alkaloids..... to get all of what Kratom is about.

Not just extract....but a cleaner and more refined "Extract" which isn't as heavy as normal regular extract. This is the strongest that can be made at Full Spectrum. If it was any stronger, it would
loose some of the other important alkaloids.

Our supplier is full cGMP.... for that we are grateful.

The best part of it is....
The "extract" we use, raises the Mitragynine levels without raising the 7-Hydroxymitragynine levels, which means
that the 7-Hydroxymitragynine is Less than 0.1%, anyone that knows Kratom, knows thats a good thing.

Each gram of our Enhanced Kratom powder has approx 4.5 mg of MIT (Mitragynine)
This is not the standard extract that many sell. Ours is more refined and to the point....you might say!*

Important: Start with less.... 2 times stronger than real good Kratom.

Come on over and check it out on either website:
https://goldleafbotanicals.net
https://insensebotanicals.com

We will soon be introducing some other stronger more potent strains.....without extract.

If you have any questions please give us a call.

Thank You Everyone for being a part of Today's
Alternative Solution!
Kratom on!

*NOTE: Note: We always recommend limiting the use of any product containing extract as it can cause tolerances to rise more quickly. This blend seems to be at least 2x stronger than our normal Kratom.....which is already Great..

The In Sense and Gold Leaf Botanicals Team
530-644-0456 Office
insensebotanicals.com
goldleafbotanicals.net






Go to IN SENSE BOTANICALS

Go to GOLD LEAF BOTANICALS

I

[Damen ck]

the 7-Hydroxymitragynine is Less than 0.1%, anyone that knows Kratom, knows thats a good thing.

It is? I always thought 7-hom was the alkaloid responsible for the euphoric like effects, and was the more desirable of the 2, especially since extract users are usually seeking that added euphoria
Lately I've been hearing that a high % of mitra isn't as critical to make a fire batch. A 0.9% mitra can be just as good as a 1.7% if the combination of other alkaloids is right. depends on what vendor you talk to I guess.

[BurntEnds]

The best part of it is....
The "extract" we use, raises the Mitragynine levels without raising the 7-Hydroxymitragynine levels, which means
that the 7-Hydroxymitragynine is Less than 0.1%, anyone that knows Kratom, knows thats a good thing.

Completely disagree with this statement that it's a good thing. Binding affinity and analgesic effects of 7ohm are orders of magnitude greater than for mit in everything I've read. I guess some of it depends on what you're looking for but as has been already stated it's the combination of all alks including many others we don't test or look at that result in whether a strain is good or not. Looking only at Mit is an incomplete and narrow point of view.

[CatfatherB]

I could see the appeal in having a higher percentage of mitragynine in the powder than 7 Ohm simply because I've read that studies demonstrated that mitragynine is converted into 7 Ohm by the liver... I've also read that there was no where near the amount of 7ohm in some samples to give a theraputic effect?? Maybe OP can explain the reason behind this better than I can?

[BurntEnds]

7ohm is in the neighborhood of 40 times more potent as far as direct antinociceptive effects than Mitra...so even 0.05%*40=2% equivalency to Mit

And it's true that it appears the Mit is probably converted into 7ohm by the cytochrome P450 pathway at least in the mouse and rat model so if even a very small percentage is converted in humans (which is not always a direct correlation) it will result in much greater effects on pain.

All of that aside, what I know is the strains that I have that have been tested for higher than average 7ohm levels result in much greater relief, at least for me. The strains that have higher levels of Mit tend to be much more stimulating. There's far more complexity going on with this plant than just the Mit. There's hundreds of research articles out there looking at interaction with various receptors but they are often looking primarily at just these two alkaloids and there's a whole host of others that we understand very little about. A quick search on Google looking for "mitragynine NCBI" or "7-oh-mitragynine NCBI" will pull up hundreds of hits.

National Center for Biotechnology Information (NCBI) or also known as Pubmed-
PubMed® comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

[INSENSE3]

Hey y’all! Thanks so much for the constructive criticism.

I’ve had kratom results that were opposite of the science. Totally impossible, based on science. But. I’m merely a consumer and supporter/advocate for long term legal status and accessibility for adults across the country. I’m not the vendor in this case. I’m representing the vendor to let people know this product is available. It’s optional. No obligation. Feedback is extremely helpful. Thank you for taking the time to post! I’ll definitely share your feedback with Rob!

The hope, for me, is less of an effect on raising tolerance, whereas the higher 7-ohm products I have used most definitely raise tolerance. No joke returning to plain leaf. Sometimes a full restart is necessary after use of extract, in my experience.

I just got my order a couple of days ago, so I have not yet been interested in curtailing use and kicking it back down to my usual favorites alone. But I am using these optional products in conjunction. I’m hoping it’s as possible tool for relief from discomfort while returning to plain leaf might.

Only the best intentions are involved here. Nothing but care for this community AND running a business that is trudging forward with cGMP compliance. It’s NOT a scam intended to misrepresent the product. He’s described it with full transparency.
I won’t say anything more about it, with respect for the website rules. We absolutely appreciate the opportunity to interact with the people here and I have personally been touched by the people here.

Really hoping everyone is doing well with health and the ongoing strains on lives. This long term trauma weigh heavy on everyone in so many different ways.

Thanks again for the feedback!

Laurie

INSENSE3

[Laurie]

Looking at “only MIT” would be ridiculous, indeed. The concept is only less than ridiculous because it is made with full spectrum, high quality product to begin with. I’m finding it to be of quality worth reordering, personally. The idea is to not raise the amount of the alkaloids known for kicking up tolerance quickly and substantially. I have not yet done a full reset to test that out - having a high pain phase and thankful for the awesome products in my rotation. Having just one type of leaf from only one vendor is also ridiculous.

It’s still absolutely optional. NO OBLIGATION

Thanks for the comments,

Laurie

INSENSE3

[gopher]

7ohm is in the neighborhood of 40 times more potent as far as direct antinociceptive effects than Mitra...so even 0.05%*40=2% equivalency to Mit

And it's true that it appears the Mit is probably converted into 7ohm by the cytochrome P450 pathway at least in the mouse and rat model so if even a very small percentage is converted in humans (which is not always a direct correlation) it will result in much greater effects on pain.

All of that aside, what I know is the strains that I have that have been tested for higher than average 7ohm levels result in much greater relief, at least for me. The strains that have higher levels of Mit tend to be much more stimulating. There's far more complexity going on with this plant than just the Mit. There's hundreds of research articles out there looking at interaction with various receptors but they are often looking primarily at just these two alkaloids and there's a whole host of others that we understand very little about. A quick search on Google looking for "mitragynine NCBI" or "7-oh-mitragynine NCBI" will pull up hundreds of hits.

7ohm is several magnitudes more analgesic than morphine even, while still be proportionally less depressive of the respiratory system. I completely agree with your post though. I'm not sure science will ever figure out the extent of why kratom does what it does differently to different people. I think it's not any different honestly. Just an example of how strong placebo can be combined with the broad range of alkaloid levels that are possible. The way chemicals effect the brain is consistent across the board, just a lot of variables to account for as far as whats there when you give it that chemical. Thanks for the info you posted.

[Back2K]

The best part of it is....
The "extract" we use, raises the Mitragynine levels without raising the 7-Hydroxymitragynine levels, which means
that the 7-Hydroxymitragynine is Less than 0.1%, anyone that knows Kratom, knows thats a good thing.

Completely disagree with this statement that it's a good thing. Binding affinity and analgesic effects of 7ohm are orders of magnitude greater than for mit in everything I've read. I guess some of it depends on what you're looking for but as has been already stated it's the combination of all alks including many others we don't test or look at that result in whether a strain is good or not. Looking only at Mit is an incomplete and narrow point of view.

I’m not a biologist or chemist but I have read more than once that Mit turns into 7ohm in your liver or whatever

[Back2K]

7ohm is in the neighborhood of 40 times more potent as far as direct antinociceptive effects than Mitra...so even 0.05%*40=2% equivalency to Mit

And it's true that it appears the Mit is probably converted into 7ohm by the cytochrome P450 pathway at least in the mouse and rat model so if even a very small percentage is converted in humans (which is not always a direct correlation) it will result in much greater effects on pain.

All of that aside, what I know is the strains that I have that have been tested for higher than average 7ohm levels result in much greater relief, at least for me. The strains that have higher levels of Mit tend to be much more stimulating. There's far more complexity going on with this plant than just the Mit. There's hundreds of research articles out there looking at interaction with various receptors but they are often looking primarily at just these two alkaloids and there's a whole host of others that we understand very little about. A quick search on Google looking for "mitragynine NCBI" or "7-oh-mitragynine NCBI" will pull up hundreds of hits.

7ohm is several magnitudes more analgesic than morphine even, while still be proportionally less depressive of the respiratory system. I completely agree with your post though. I'm not sure science will ever figure out the extent of why kratom does what it does differently to different people. I think it's not any different honestly. Just an example of how strong placebo can be combined with the broad range of alkaloid levels that are possible. The way chemicals effect the brain is consistent across the board, just a lot of variables to account for as far as whats there when you give it that chemical. Thanks for the info you posted.

Some of the other alkaloids from white vein or fast strains may also be what gives Akkuama or Hirsuta or Javanica
It’s effects despite no mit, but I haven’t done extensive research!

[IndelibleDotInk]

PM'd re:samples, have not gotten a response.

[INSENSE3]

PM’d back. My apologies for the delayed reply.

Laurie

INSENSE3